差异代谢物筛选
通过对代谢物进行筛选，寻找差异代谢物（biomarker）。相关差异代谢物筛选条件有：
  1. p-value ≤ 0.05 且 VIP ≥ 1[1]
  2. p-value ≤ 0.05 且 fold_change ≥ 1.5或≤0.667[2]
  3. one-way ANOVA p-value ≤ 0.05[3]
  4. two-way ANOVA p-value ≤ 0.05[4]
详细含义：
筛选值 筛选值含义 筛选阈值 备注
p-value 统计学上显著差异 p-value ≤ 0.05 无
VIP OPLS-DA第一主成分变量重要性值投影 VIP ≥ 1 无
Fold change 两两组别间倍性变化 fold_change ≥1.5或≤0.667 含量差异较大
one-way ANOVA p-value 一维方差分析 p-value ≤ 0.05 主要用于时间序列，梯度浓度处理等
two-way ANOVA p-value 两因素方差分析 p-value ≤ 0.05 一般为两因素情况，如对照-处理+时间序列样本
本实验采用条件 1 进行代谢物筛选，最终获得的差异代谢物见下表：

差异信息汇总信息
差异信息汇总表格；dam_DEG.xlsx （正离子模式）
dam_DEG.xlsx 包含“stats”和“ALL_DEG.xlsx”两个工作簿，其中“stats”统计了各个比对组别差异代谢物的上、下调情况，“ALL_DEG”汇总了所有比对组别的差异代谢物信息。

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mz rt rtmin VIP mean_Pre-E-b sd_Pre-E-b mean_Con-b sd_Con-b Fold Change_Pre-E-b/Con-b log2(FC_Pre-E-b/Con-b) p.value FDR
M83T744 83.061 743.691 12.390 1.399 75.641 0.000 581605178.145 472293588.464 0.000 -22.874 0.003 0.034
M83T379 83.375 378.947 6.320 1.932 75.641 0.000 208270.410 51202.750 0.000 -11.427 0.003 0.034
M84T802 84.045 802.125 13.370 1.385 75.641 0.000 1812253.650 1498783.189 0.000 -14.548 0.003 0.034
M84T488 84.045 488.370 8.140 1.377 75.641 0.000 10138923.762 8477437.576 0.000 -17.032 0.003 0.034
M84T719 84.064 719.157 11.990 1.432 619788.921 480616.035 75.641 0.000 8193.900 13.000 0.003 0.034
M85T73 84.960 73.118 1.220 1.489 75.641 0.000 18379394.164 13148236.625 0.000 -17.890 0.003 0.034
M88T743 88.076 742.630 12.380 1.666 75.641 0.000 21217615.336 11375703.167 0.000 -18.098 0.003 0.034
M88T825 88.076 824.536 13.740 1.936 75.641 0.000 20140104.972 4834198.527 0.000 -18.022 0.003 0.034
M88T532 88.076 532.467 8.870 1.833 75.641 0.000 26986510.293 9845664.787 0.000 -18.445 0.003 0.034
M88T591 88.076 591.463 9.860 1.357 75.641 0.000 29170238.069 25069512.863 0.000 -18.557 0.003 0.034
M89T73 88.521 73.223 1.220 1.660 75.641 0.000 4515406.887 2447976.850 0.000 -15.865 0.003 0.034
M90T68 89.507 68.452 1.140 1.915 75.641 0.000 10883855.020 2917068.290 0.000 -17.135 0.003 0.034
M90T36 90.008 35.602 0.590 1.268 75.641 0.000 1885614.170 1820286.654 0.000 -14.606 0.003 0.034
M91T660 90.977 659.731 11.000 1.629 3603574.393 2067237.786 75.641 0.000 47641.000 15.540 0.003 0.034
M97T798 96.753 798.192 13.300 1.991 75.641 0.000 444002.592 65383.832 0.000 -12.519 0.003 0.034
M97T755 97.076 755.095 12.580 1.337 75.641 0.000 16866507.812 14885583.722 0.000 -17.767 0.003 0.034
M97T834 97.076 834.145 13.900 1.896 75.641 0.000 11137926.469 3256204.855 0.000 -17.168 0.003 0.034
M98T54 97.992 54.460 0.910 1.972 75.641 0.000 1150349.756 210051.634 0.000 -13.893 0.003 0.034
M98T69 98.014 68.859 1.150 1.079 75.641 0.000 9109295.264 11216635.094 0.000 -16.878 0.003 0.034
M101T828 101.071 827.929 13.800 1.429 25101283.091 19552122.627 75.641 0.000 331850.000 18.340 0.003 0.034
M102T74 102.055 74.039 1.230 1.160 75.641 0.000 1774993.786 1969431.990 0.000 -14.518 0.003 0.034
M103T73_2 102.971 73.193 1.220 1.456 75.641 0.000 16646823.009 12481935.130 0.000 -17.748 0.003 0.034
M104T73 104.031 73.116 1.220 1.537 75.641 0.000 2580474.022 1716428.000 0.000 -15.058 0.003 0.034
M105T675 105.042 674.715 11.250 1.782 75.641 0.000 19962604.015 8366065.934 0.000 -18.010 0.003 0.034
M105T648 105.042 647.814 10.800 1.012 75.641 0.000 12101449.743 16267044.421 0.000 -17.288 0.003 0.034
M108T76 107.967 76.026 1.270 1.742 75.641 0.000 3363450.395 1547312.277 0.000 -15.440 0.003 0.034
M110T748 110.020 748.496 12.470 1.118 75.641 0.000 182518321.030 213727240.218 0.000 -21.202 0.003 0.034
M110T529 110.021 529.083 8.820 1.868 75.641 0.000 117152526.397 38118607.746 0.000 -20.563 0.003 0.034
M111T73_1 111.021 73.300 1.220 1.452 75.641 0.000 20389206.432 15366448.409 0.000 -18.040 0.003 0.034
M112T80 112.461 80.085 1.330 1.705 75.641 0.000 1798353.641 894953.848 0.000 -14.537 0.003 0.034
M113T714 113.017 714.095 11.900 1.715 75.641 0.000 17973164.720 8763419.542 0.000 -17.858 0.003 0.034
M113T100 113.035 100.317 1.670 1.483 75.641 0.000 49413923.531 35645221.347 0.000 -19.317 0.003 0.034
M113T734 113.034 734.216 12.240 1.811 75.641 0.000 4410780.212 1717810.260 0.000 -15.832 0.003 0.034
M113T468 113.035 468.213 7.800 1.645 75.641 0.000 5646484.362 3148269.370 0.000 -16.188 0.003 0.034
M114T231 113.964 231.187 3.850 1.555 29785406.208 19270344.607 75.641 0.000 393780.000 18.587 0.003 0.034
M114T178_2 114.065 177.923 2.970 1.840 75.641 0.000 54631811.358 19538352.625 0.000 -19.462 0.003 0.034
M114T791 114.066 791.184 13.190 1.772 75.641 0.000 16930902.298 7285598.702 0.000 -17.772 0.003 0.034
M114T111 114.067 111.371 1.860 1.273 75.641 0.000 59375701.279 56955678.223 0.000 -19.582 0.003 0.034
M114T303 114.065 303.072 5.050 1.525 75.641 0.000 34639290.591 23493831.598 0.000 -18.805 0.003 0.034
M115T71 114.559 71.411 1.190 1.448 75.641 0.000 385087.170 292154.232 0.000 -12.314 0.003 0.034
M116T73 116.002 73.148 1.220 1.651 75.641 0.000 24501751.911 13503636.337 0.000 -18.305 0.003 0.034
M117T150 116.966 149.660 2.490 1.373 75.641 0.000 16135480.865 13577386.418 0.000 -17.703 0.003 0.034
M117T231 116.966 231.142 3.850 1.510 75.641 0.000 28815759.924 19976936.813 0.000 -18.539 0.003 0.034
M117T132 116.966 132.329 2.210 1.535 75.641 0.000 3210832.715 2143857.163 0.000 -15.373 0.003 0.034
M119T173 119.049 173.232 2.890 1.509 75.641 0.000 4500417.506 3126279.615 0.000 -15.861 0.003 0.034
M120T402 120.076 402.359 6.710 1.789 75.641 0.000 1832613.682 754779.681 0.000 -14.564 0.003 0.034
M121T73 120.981 72.759 1.210 1.487 75.641 0.000 35416542.110 25407070.143 0.000 -18.837 0.003 0.034
M122T344_1 122.059 344.120 5.740 1.494 75.641 0.000 11280226.850 8013086.427 0.000 -17.186 0.003 0.034
M123T73 122.547 72.674 1.210 1.604 75.641 0.000 14829909.358 8871391.527 0.000 -17.581 0.003 0.034
M127T39 126.956 39.071 0.650 1.142 75.641 0.000 49945152.501 56732819.728 0.000 -19.333 0.003 0.034
M127T466 127.040 465.699 7.760 1.446 75.641 0.000 31754193.838 24161935.643 0.000 -18.679 0.003 0.034
M127T289 127.039 289.464 4.820 1.458 75.641 0.000 70240396.884 52533504.820 0.000 -19.825 0.003 0.034
M128T779 128.089 778.548 12.980 1.667 75.641 0.000 9880527.622 5290289.025 0.000 -16.995 0.003 0.034
M130T602 130.065 602.326 10.040 1.938 75.641 0.000 7342113.705 1741137.991 0.000 -16.567 0.003 0.034
M131T602 131.069 602.323 10.040 1.759 75.641 0.000 391278.446 173570.035 0.000 -12.337 0.003 0.034
M132T236 131.974 236.017 3.930 1.807 75.641 0.000 28770465.154 11329424.126 0.000 -18.537 0.003 0.034
M132T73 132.066 72.798 1.210 1.771 75.641 0.000 17004159.051 7328758.074 0.000 -17.778 0.003 0.034
M133T703 132.531 703.498 11.720 1.488 75.641 0.000 3838686.075 2751089.021 0.000 -15.631 0.003 0.034
M133T831 133.033 830.861 13.850 1.469 75.641 0.000 919216.551 676793.160 0.000 -13.569 0.003 0.034
M138T246 137.986 245.993 4.100 1.340 75.641 0.000 36395250.413 31968094.229 0.000 -18.876 0.003 0.034
M139T98 138.906 98.411 1.640 1.713 75.641 0.000 6445018.200 3156005.909 0.000 -16.379 0.003 0.034
M140T705 139.989 704.510 11.740 1.385 75.641 0.000 15001794.404 12418152.501 0.000 -17.598 0.003 0.034
M140T142 140.070 142.267 2.370 1.432 75.641 0.000 14163934.892 10983594.507 0.000 -17.515 0.003 0.034
M142T102_1 142.049 101.922 1.700 1.695 75.641 0.000 7005021.297 3558349.008 0.000 -16.499 0.003 0.034
M142T66 142.123 65.613 1.090 1.467 75.641 0.000 3124307.501 2307488.810 0.000 -15.334 0.003 0.034
M143T162 142.520 162.144 2.700 1.269 454886.646 438655.215 75.641 0.000 6013.800 12.554 0.003 0.034
M143T58 143.040 57.506 0.960 1.380 75.641 0.000 12440792.770 10360588.345 0.000 -17.327 0.003 0.034
M143T266 143.040 265.940 4.430 1.489 75.641 0.000 14543997.764 10396716.348 0.000 -17.553 0.003 0.034
M144T73_1 143.997 73.193 1.220 1.535 75.641 0.000 104002883.933 69425743.338 0.000 -20.391 0.003 0.034
M145T149 144.961 149.101 2.490 1.863 75.641 0.000 8695812.921 2880093.661 0.000 -16.811 0.003 0.034
M145T229 145.032 229.044 3.820 1.428 75.641 0.000 12825423.598 9998740.318 0.000 -17.371 0.003 0.034
M145T90_1 145.049 89.669 1.490 1.798 75.641 0.000 10155658.696 4092034.665 0.000 -17.035 0.003 0.034
M145T694 145.142 693.773 11.560 1.954 75.641 0.000 145697.874 30953.657 0.001 -10.912 0.003 0.034
M147T828 146.981 827.937 13.800 1.237 75.641 0.000 43187127.016 43385438.416 0.000 -19.123 0.003 0.034
M149T257 149.021 256.962 4.280 2.003 75.641 0.000 8989267.053 1079679.484 0.000 -16.859 0.003 0.034
M149T214_2 149.067 214.286 3.570 1.952 579552.410 125314.171 75.641 0.000 7661.900 12.903 0.003 0.034
M149T738 149.133 737.752 12.300 1.480 75.641 0.000 819442.645 593633.650 0.000 -13.403 0.003 0.034
M152T297 152.057 296.675 4.940 1.952 75.641 0.000 427803.910 92332.024 0.000 -12.466 0.003 0.034
M153T76 152.947 75.502 1.260 1.424 75.641 0.000 6874305.190 5395344.496 0.000 -16.472 0.003 0.034
M157T408 157.084 408.010 6.800 1.227 75.641 0.000 727056.128 740489.205 0.000 -13.231 0.003 0.034
M157T85_3 157.170 84.576 1.410 1.774 75.641 0.000 109407.517 46776.983 0.001 -10.498 0.003 0.034
M158T72 157.989 72.293 1.200 1.575 75.641 0.000 2605788.596 1633753.285 0.000 -15.072 0.003 0.034
M158T378 158.088 377.822 6.300 1.449 75.641 0.000 3635185.919 2754244.607 0.000 -15.553 0.003 0.034
M158T104 158.154 103.589 1.730 2.018 75.641 0.000 20265909.937 1420932.215 0.000 -18.031 0.003 0.034
M158T745 158.153 744.928 12.420 1.704 75.641 0.000 14631924.178 7299614.663 0.000 -17.562 0.003 0.034
M159T100 158.961 99.942 1.670 1.794 75.641 0.000 3663942.574 1491086.836 0.000 -15.564 0.003 0.034
M159T285 158.961 284.927 4.750 1.580 75.641 0.000 22787635.113 14184147.434 0.000 -18.201 0.003 0.034
M161T73 160.987 73.037 1.220 1.627 75.641 0.000 4343394.413 2496370.963 0.000 -15.809 0.003 0.034
M162T142_1 161.961 141.903 2.370 1.589 1290865.451 791362.501 75.641 0.000 17066.000 14.059 0.003 0.034
M162T407 162.002 407.034 6.780 1.663 75.641 0.000 10183920.891 5496862.707 0.000 -17.039 0.003 0.034
M162T471 162.003 470.601 7.840 1.503 75.641 0.000 9480755.624 6637956.746 0.000 -16.935 0.003 0.034
M162T71 162.002 71.002 1.180 1.759 75.641 0.000 4903014.101 2173549.602 0.000 -15.984 0.003 0.034
M163T142 163.053 141.988 2.370 1.138 75.641 0.000 2512141.439 2865856.338 0.000 -15.019 0.003 0.034
M166T117 166.018 116.540 1.940 1.855 75.641 0.000 19991416.023 6803232.416 0.000 -18.012 0.003 0.034
M167T338 167.056 338.167 5.640 1.162 75.641 0.000 8338562.157 9225121.326 0.000 -16.750 0.003 0.034
M167T198 167.058 198.460 3.310 1.477 75.641 0.000 1593956.517 1160071.664 0.000 -14.363 0.003 0.034
M168T609 168.042 609.483 10.160 1.515 75.641 0.000 353478.519 243096.120 0.000 -12.190 0.003 0.034
M169T756 168.999 756.201 12.600 1.518 75.641 0.000 11828212.010 8097375.473 0.000 -17.255 0.003 0.034
M169T308 169.048 307.525 5.130 1.004 75.641 0.000 5305836.226 7203429.391 0.000 -16.098 0.003 0.034
M170T116_1 170.010 115.721 1.930 1.884 75.641 0.000 14523089.918 4449712.027 0.000 -17.551 0.003 0.034
M171T481 171.148 480.835 8.010 1.247 75.641 0.000 54146810.037 53696946.126 0.000 -19.449 0.003 0.034
M171T456 171.148 456.245 7.600 1.710 75.641 0.000 47744773.465 23522125.192 0.000 -19.268 0.003 0.034
M172T114 172.040 113.645 1.890 1.851 75.641 0.000 5019115.745 1730248.816 0.000 -16.018 0.003 0.034
M173T64 173.000 64.369 1.070 1.947 75.641 0.000 1647409.902 368172.884 0.000 -14.411 0.003 0.034
M173T126 173.004 125.513 2.090 1.757 75.641 0.000 3524381.300 1570515.154 0.000 -15.508 0.003 0.034
M175T246 175.048 245.670 4.090 1.484 75.641 0.000 4144926.483 2985604.685 0.000 -15.742 0.003 0.034
M177T102 177.131 101.815 1.700 1.600 75.641 0.000 539024.052 324340.395 0.000 -12.799 0.003 0.034
M178T714 178.159 714.169 11.900 1.720 75.641 0.000 399012.891 192461.341 0.000 -12.365 0.003 0.034
M178T666 178.159 665.963 11.100 1.937 75.641 0.000 358736.467 85208.108 0.000 -12.211 0.003 0.034
M182T817 182.019 817.457 13.620 1.729 2433542.521 1152780.481 75.641 0.000 32172.000 14.974 0.003 0.034
M183T67 182.985 67.365 1.120 1.634 590310204.001 335344481.916 75.641 0.000 7804200.000 22.896 0.003 0.034
M183T817 182.985 816.942 13.620 1.333 75.641 0.000 15500460.267 13743593.231 0.000 -17.645 0.003 0.034
M183T311 182.984 310.681 5.180 1.461 75.641 0.000 112619816.298 83854575.029 0.000 -20.506 0.003 0.034
M183T656 182.983 656.019 10.930 2.016 75.641 0.000 42055355.508 3371399.747 0.000 -19.085 0.003 0.034
M184T274 183.996 273.587 4.560 1.895 1037127.673 304949.997 75.641 0.000 13711.000 13.743 0.003 0.034
M184T62 184.008 62.208 1.040 1.665 75.641 0.000 3411887.070 1832179.130 0.000 -15.461 0.003 0.034
M187T771 186.981 771.261 12.850 1.344 75.641 0.000 36492233.533 31906953.616 0.000 -18.880 0.003 0.034
M187T758 186.981 757.881 12.630 1.171 75.641 0.000 4397798.982 4814012.985 0.000 -15.827 0.003 0.034
M187T826 187.125 825.975 13.770 1.632 75.641 0.000 6044479.350 3447178.888 0.000 -16.286 0.003 0.034
M188T664 188.047 664.158 11.070 1.935 75.641 0.000 768158.979 185445.809 0.000 -13.310 0.003 0.034
M190T99 189.959 99.002 1.650 1.525 75.641 0.000 1204102.084 816105.586 0.000 -13.958 0.003 0.034
M190T214 190.046 213.706 3.560 1.878 75.641 0.000 509708.958 160351.845 0.000 -12.718 0.003 0.034
M191T159 190.993 158.792 2.650 1.460 75.641 0.000 98445130.969 73388495.895 0.000 -20.312 0.003 0.034
M191T93 191.150 92.556 1.540 1.154 75.641 0.000 882647.363 986466.601 0.000 -13.510 0.003 0.034
M192T227 192.040 226.994 3.780 1.900 75.641 0.000 1155579.072 331924.398 0.000 -13.899 0.003 0.034
M193T446 193.138 446.409 7.440 1.634 75.641 0.000 19127207.769 10873656.803 0.000 -17.948 0.003 0.034
M196T80 196.102 80.086 1.330 1.637 75.641 0.000 1445961.509 817774.995 0.000 -14.223 0.003 0.034
M197T117 197.009 117.137 1.950 1.661 75.641 0.000 20823346.721 11278907.042 0.000 -18.071 0.003 0.034
M197T32 197.096 32.216 0.540 1.888 75.641 0.000 929369.866 280755.806 0.000 -13.585 0.003 0.034
M198T826 198.185 825.577 13.760 1.966 75.641 0.000 8061847.425 1564794.640 0.000 -16.702 0.003 0.034
M199T84 198.710 84.489 1.410 1.741 75.641 0.000 5747202.385 2651409.447 0.000 -16.213 0.003 0.034
M199T113 199.008 113.070 1.880 1.847 75.641 0.000 1308296.939 457288.841 0.000 -14.078 0.003 0.034
M199T597 199.152 596.840 9.950 1.662 75.641 0.000 186024.924 100569.115 0.000 -11.264 0.003 0.034
M200T151_1 199.988 150.773 2.510 1.950 75.641 0.000 34689961.005 7624789.584 0.000 -18.807 0.003 0.034
M200T338 199.988 338.100 5.640 1.497 75.641 0.000 9781495.000 6909971.551 0.000 -16.981 0.003 0.034
M202T437_1 202.043 437.454 7.290 1.527 75.641 0.000 706725.604 477675.745 0.000 -13.190 0.003 0.034
M202T106 202.107 105.588 1.760 1.980 75.641 0.000 10609095.140 1794467.406 0.000 -17.098 0.003 0.034
M204T142 204.056 142.222 2.370 1.676 4940221.545 2602022.936 75.641 0.000 65312.000 15.995 0.003 0.034
M207T737 207.174 736.587 12.280 1.623 75.641 0.000 365326.823 211597.440 0.000 -12.238 0.003 0.034
M210T65 209.999 65.290 1.090 1.064 75.641 0.000 3853345.369 4838027.335 0.000 -15.637 0.003 0.034
M211T579 211.094 579.279 9.650 1.897 75.641 0.000 4937192.842 1439564.706 0.000 -15.994 0.003 0.034
M213T723 213.147 722.701 12.050 1.874 75.641 0.000 6778652.494 2164829.162 0.000 -16.451 0.003 0.034
M214T38 213.983 37.603 0.630 1.938 2140405.413 505740.500 75.641 0.000 28297.000 14.788 0.003 0.034
M215T75 215.088 75.247 1.250 1.465 75.641 0.000 1641337.118 1214499.347 0.000 -14.405 0.003 0.034
M216T597 216.159 596.884 9.950 1.921 75.641 0.000 2366836.807 617331.266 0.000 -14.933 0.003 0.034
M217T65 216.920 64.811 1.080 1.875 75.641 0.000 2410761.130 764535.854 0.000 -14.960 0.003 0.034
M217T130 216.922 130.315 2.170 1.590 75.641 0.000 1952470.136 1194698.261 0.000 -14.656 0.003 0.034
M218T378 218.139 378.276 6.300 1.800 75.641 0.000 371183.611 148789.207 0.000 -12.261 0.003 0.034
M219T820 219.174 819.787 13.660 1.387 75.641 0.000 2447834.414 2020403.279 0.000 -14.982 0.003 0.034
M222T410 222.060 410.495 6.840 1.338 75.641 0.000 320202.227 282213.476 0.000 -12.048 0.003 0.034
M223T138 222.879 137.838 2.300 1.261 75.641 0.000 468062.385 456172.193 0.000 -12.595 0.003 0.034
M223T718_1 223.007 717.514 11.960 1.486 75.641 0.000 109750.730 78752.002 0.001 -10.503 0.003 0.034
M223T451 223.154 450.934 7.520 2.010 75.641 0.000 1735199.689 171841.031 0.000 -14.486 0.003 0.034
M224T274 224.024 274.146 4.570 1.841 75.641 0.000 1303374.748 464746.246 0.000 -14.073 0.003 0.034
M224T761 224.063 760.953 12.680 1.977 75.641 0.000 1231109.905 214440.964 0.000 -13.990 0.003 0.034
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M147T774 147.080 773.548 12.890 1.614 12127731.492 5934271.800 1870191.667 1109071.859 6.485 2.697 0.005 0.034
M148T86 148.004 86.087 1.430 1.277 11314180.423 3555644.865 6708957.013 2579970.267 1.686 0.754 0.005 0.034
M148T144_1 148.041 144.260 2.400 1.524 1433663.763 594904.917 11644847.814 6902766.520 0.123 -3.022 0.005 0.034
M149T84 148.935 84.041 1.400 1.686 47670499.432 7874239.329 32284152.638 1086627.219 1.477 0.562 0.005 0.034
M149T109 149.003 108.883 1.810 1.581 265590.574 108853.577 3869932.252 2235823.681 0.069 -3.865 0.005 0.034
M149T570 149.045 570.177 9.500 1.508 1493310.000 238518.814 1855002.129 79498.635 0.805 -0.313 0.005 0.034
M150T36 149.966 36.418 0.610 1.642 1900242.707 426220.590 9374659.138 4166253.067 0.203 -2.303 0.005 0.034
M151T144_1 151.018 143.772 2.400 1.627 1340654.661 445067.381 5704470.194 2470295.600 0.235 -2.089 0.005 0.034
M153T36_1 152.995 36.060 0.600 1.356 13737518.487 4489920.302 68651140.718 47021028.021 0.200 -2.321 0.005 0.034
M153T536 153.054 536.184 8.940 1.448 1555247.423 1106328.175 9111336.019 5627009.293 0.171 -2.550 0.005 0.034
M154T140 153.956 139.607 2.330 1.329 148753.444 43360.697 2000289.818 1650565.170 0.074 -3.749 0.005 0.034
M154T34 153.993 34.037 0.570 1.852 19548530.832 2582848.120 9473719.127 2305798.192 2.063 1.045 0.005 0.034
M154T126 153.998 126.025 2.100 1.364 256806599.600 58574231.906 1188263689.832 791088205.497 0.216 -2.210 0.005 0.034
M154T72 154.036 71.975 1.200 1.389 9768730.390 5803755.914 2698891.790 426343.555 3.619 1.856 0.005 0.034
M154T476 154.041 476.175 7.940 1.418 2833001.684 93613.009 2390111.100 337393.894 1.185 0.245 0.005 0.034
M154T402_3 154.093 402.413 6.710 1.029 1112168.565 251841.622 4541994.696 4502185.111 0.245 -2.030 0.005 0.034
M155T315 154.990 315.450 5.260 1.352 185244355.000 110539851.463 859799092.923 573226451.772 0.215 -2.215 0.005 0.034
M155T473 154.988 472.846 7.880 1.510 15741632.469 11222107.368 77552988.284 41370824.866 0.203 -2.301 0.005 0.034
M155T91 155.010 91.390 1.520 1.207 587817.662 149715.783 2943887.624 2457714.618 0.200 -2.324 0.005 0.034
M155T402 155.045 402.356 6.710 1.844 135168476.243 7722028.644 111672833.331 3018090.286 1.210 0.275 0.005 0.034
M155T731 155.143 730.645 12.180 1.787 516115.780 232667.878 1819678.393 486789.910 0.284 -1.818 0.005 0.034
M156T587 156.039 587.159 9.790 1.753 965155.290 43667.104 1167173.558 79528.709 0.827 -0.274 0.005 0.034
M157T78_1 156.948 77.728 1.300 1.073 746946.296 134455.193 2907166.160 2677466.742 0.257 -1.960 0.005 0.034
M157T81 157.047 81.304 1.360 1.801 4787881.171 957482.610 2021432.816 550157.351 2.369 1.244 0.005 0.034
M157T88 157.122 88.127 1.470 1.352 957838.917 565733.660 12734600.309 10164336.786 0.075 -3.733 0.005 0.034
M158T454 158.002 453.517 7.560 1.717 5622456.789 3222049.602 45132795.904 18913312.303 0.125 -3.005 0.005 0.034
M159T81_2 158.963 81.324 1.360 1.903 621424248.468 10998262.767 698536033.225 18953378.708 0.890 -0.169 0.005 0.034
M159T113 159.013 112.828 1.880 1.812 22386747.333 988074.295 27195727.118 1579548.872 0.823 -0.281 0.005 0.034
M159T102 159.120 101.904 1.700 1.388 2896496.506 1591180.748 950284.345 201197.756 3.048 1.608 0.005 0.034
M159T153 159.157 153.257 2.550 1.798 1873133.725 194805.393 3205036.498 499672.229 0.584 -0.775 0.005 0.034
M160T113 160.013 112.683 1.880 1.130 952442.767 219470.042 3064121.866 2423903.607 0.311 -1.686 0.005 0.034
M160T63 160.097 63.446 1.060 1.280 288268.212 114933.186 6466814.715 5874422.386 0.045 -4.488 0.005 0.034
M161T71 161.029 71.450 1.190 1.378 5950956.970 3769737.029 1407581.322 433870.547 4.228 2.080 0.005 0.034
M161T708 161.112 708.244 11.800 1.071 171928.319 74542.429 700014.305 652932.488 0.246 -2.026 0.005 0.034
M162T36 162.002 35.895 0.600 1.796 19758691.434 2892539.046 11658265.772 1546041.548 1.695 0.761 0.005 0.034
M162T607 162.091 607.170 10.120 1.766 140657.264 34355.326 1583940.565 627967.416 0.089 -3.493 0.005 0.034
M163T36 162.998 35.848 0.600 1.739 87812224.921 11861569.839 120888176.365 9734614.682 0.726 -0.461 0.005 0.034
M163T339 163.087 339.324 5.660 1.796 368114.719 74131.410 788399.367 152943.576 0.467 -1.099 0.005 0.034
M163T581 163.133 580.937 9.680 1.782 10539990.011 3346198.442 2496610.207 432615.959 4.222 2.078 0.005 0.034
M163T561_2 163.480 561.069 9.350 1.461 172813.556 64929.534 1442614.050 942661.119 0.120 -3.061 0.005 0.034
M164T36 163.998 35.975 0.600 1.842 13219126.036 1635527.951 7589546.659 1154554.962 1.742 0.801 0.005 0.034
M164T745 164.115 744.992 12.420 1.650 11453195.676 2806656.023 5892201.643 1242157.654 1.944 0.959 0.005 0.034
M165T402 165.010 402.361 6.710 1.159 23508676.821 22095806.190 3609635.646 598489.125 6.513 2.703 0.005 0.034
M165T72 165.068 71.513 1.190 1.562 13591555.769 6749783.719 2987537.076 751934.064 4.549 2.186 0.005 0.034
M166T37 165.983 37.255 0.620 1.902 16239701.632 3059662.215 5313125.908 586750.063 3.057 1.612 0.005 0.034
M166T102_1 166.072 102.283 1.700 1.481 2197030.977 357959.987 1425771.942 428383.713 1.541 0.624 0.005 0.034
M166T327 166.072 327.411 5.460 1.709 283717.362 55639.825 127808.280 53146.484 2.220 1.151 0.005 0.034
M170T67 169.976 67.204 1.120 1.966 100021459.633 12381481.649 30072914.226 5508626.778 3.326 1.734 0.005 0.034
M170T86 169.986 86.077 1.430 1.437 16077932.097 5899428.000 6890374.151 3906386.719 2.333 1.222 0.005 0.034
M170T132 170.039 131.745 2.200 1.446 957127.440 401208.117 7413605.760 4893334.088 0.129 -2.953 0.005 0.034
M170T814 170.056 814.490 13.570 1.443 8932511.235 409899.652 10909224.737 1452647.327 0.819 -0.288 0.005 0.034
M170T400 170.060 400.081 6.670 1.565 13758100.593 2821651.702 8581420.801 1712157.651 1.603 0.681 0.005 0.034
M170T828 170.096 828.435 13.810 1.466 77532823.684 2522671.143 87634103.788 7026892.838 0.885 -0.177 0.005 0.034
M171T115 170.983 115.133 1.920 1.356 698777.176 324187.256 2197707.423 1247469.663 0.318 -1.653 0.005 0.034
M171T400 171.063 399.524 6.660 1.301 882758.849 270384.426 2342325.455 1322976.030 0.377 -1.408 0.005 0.034
M171T460 171.100 459.975 7.670 1.649 10228404.617 753000.416 16628024.137 3463363.928 0.615 -0.701 0.005 0.034
M171T699 171.117 699.399 11.660 1.977 202807.703 64280.103 747645.465 69773.654 0.271 -1.882 0.005 0.034
M171T133 171.148 132.810 2.210 1.622 5278113.504 4313945.001 80523364.978 43422754.398 0.066 -3.931 0.005 0.034
M171T535 171.148 535.281 8.920 1.325 7204834.657 3865001.058 100821036.872 83804357.990 0.071 -3.807 0.005 0.034
M172T150 172.040 150.264 2.500 1.715 20825095.280 5400824.533 8767819.860 2334493.258 2.375 1.248 0.005 0.034
M173T783 173.173 783.116 13.050 1.700 641062.451 272417.756 1328075.105 212484.899 0.483 -1.051 0.005 0.034
M174T109 173.959 109.219 1.820 1.732 872151.910 207646.710 4685031.996 1782104.742 0.186 -2.425 0.005 0.034
M174T163 174.014 162.588 2.710 1.287 84232559.649 58819420.922 21241771.256 8094076.125 3.965 1.988 0.005 0.034
M174T603 174.055 603.408 10.060 1.848 123128.176 20575.432 719897.117 206780.331 0.171 -2.548 0.005 0.034
M174T143 174.050 143.180 2.390 1.164 262706.352 110307.999 985858.918 790741.805 0.266 -1.908 0.005 0.034
M174T310 174.082 309.942 5.170 1.828 1301247.740 285039.719 6082074.349 1749645.073 0.214 -2.225 0.005 0.034
M175T81 175.034 81.316 1.360 1.423 10568034.651 7147185.232 1409301.434 779140.762 7.499 2.907 0.005 0.034
M176T93 176.067 93.427 1.560 1.384 7381563.704 5679886.209 523894.984 140940.712 14.090 3.817 0.005 0.034
M177T561_1 176.821 561.082 9.350 1.041 7669060.509 9295884.835 488032.669 122601.497 15.714 3.974 0.005 0.034
M178T623 178.159 622.964 10.380 1.844 211380.609 80191.883 1454371.211 431640.004 0.145 -2.783 0.005 0.034
M180T112 180.034 111.688 1.860 1.855 19606245.342 839507.433 23803794.886 1158208.305 0.824 -0.280 0.005 0.034
M180T81 180.063 81.381 1.360 1.874 1832448.766 583717.472 6026701.888 1204893.091 0.304 -1.718 0.005 0.034
M180T451 180.100 450.637 7.510 1.544 1076790.816 560859.619 2462769.949 719899.964 0.437 -1.194 0.005 0.034
M181T67 180.990 67.304 1.120 1.939 14393715.138 4877382.780 35745643.247 1237377.644 0.403 -1.312 0.005 0.034
M181T81_1 181.047 80.690 1.340 1.252 27101743.116 22115977.321 4618896.231 1631817.197 5.868 2.553 0.005 0.034
M182T162 181.992 162.086 2.700 1.789 2804943.868 1731259.919 17797800.100 5928484.265 0.158 -2.666 0.005 0.034
M182T214 181.992 213.961 3.570 1.445 414837.360 336515.153 2921834.144 1879440.880 0.142 -2.816 0.005 0.034
M183T461 182.983 460.901 7.680 1.407 213392212.110 127353629.215 51987295.930 24196433.581 4.105 2.037 0.005 0.034
M183T36 183.030 36.406 0.610 1.879 3747413.420 293042.506 2172961.924 395906.352 1.725 0.786 0.005 0.034
M183T816_2 183.080 815.838 13.600 1.699 40881917.044 4137795.012 51711398.879 3547115.650 0.791 -0.339 0.005 0.034
M183T721 183.116 721.451 12.020 1.255 313489.700 130901.381 708546.679 365201.105 0.442 -1.176 0.005 0.034
M184T832 184.072 831.991 13.870 1.630 119451899.821 35080514.613 47674177.776 21387963.061 2.506 1.325 0.005 0.034
M185T461 185.045 461.037 7.680 1.532 3815375.635 1995853.841 828231.458 185149.568 4.607 2.204 0.005 0.034
M186T71 186.036 71.003 1.180 1.529 5941850.351 2325012.052 2375208.340 610143.257 2.502 1.323 0.005 0.034
M186T580 186.119 580.472 9.670 1.753 4458876.535 519575.906 3188156.328 236342.122 1.399 0.484 0.005 0.034
M186T604 186.221 604.141 10.070 1.783 9982587.372 596183.021 8431143.094 257793.264 1.184 0.244 0.005 0.034
M187T713 186.981 713.317 11.890 1.445 1003168.445 643888.885 6781483.632 4356144.462 0.148 -2.757 0.005 0.034
M187T365 187.094 365.019 6.080 1.848 31023886.773 3084401.016 19397457.294 2623819.446 1.599 0.678 0.005 0.034
M187T717 187.125 716.659 11.940 1.793 2022813.129 1455056.537 13346920.142 4385520.177 0.152 -2.722 0.005 0.034
M188T143 187.991 143.290 2.390 1.766 665220.338 287653.505 3485277.268 1196888.457 0.191 -2.389 0.005 0.034
M188T400_1 188.002 399.585 6.660 1.579 3367167.814 1347150.746 1177928.645 217078.803 2.858 1.515 0.005 0.034
M188T71 188.052 71.439 1.190 1.439 3569740.701 2000996.877 911733.527 408968.940 3.915 1.969 0.005 0.034
M188T519 188.071 518.605 8.640 1.906 1994360.299 315769.399 616180.454 219916.380 3.237 1.694 0.005 0.034
M189T66 188.998 66.389 1.110 1.687 1905974.348 1250883.799 5842790.544 1596795.806 0.326 -1.616 0.005 0.034
M189T432 189.096 432.204 7.200 1.378 155950.288 34196.297 565202.842 340165.899 0.276 -1.858 0.005 0.034
M189T303 189.123 303.422 5.060 1.566 5163462.256 2768235.726 734440.538 534134.232 7.030 2.814 0.005 0.034
M190T143_1 189.956 143.015 2.380 1.312 395421.866 156812.244 1606759.836 1093355.301 0.246 -2.023 0.005 0.034
M190T68 189.997 67.650 1.130 1.788 1449747.502 458515.398 6860624.451 2187823.442 0.211 -2.243 0.005 0.034
M190T283 190.046 282.945 4.720 1.706 2458791.285 945731.931 458592.575 302813.206 5.362 2.423 0.005 0.034
M191T38 190.979 37.883 0.630 1.129 803323.440 374561.278 39637644.002 44843372.079 0.020 -5.625 0.005 0.034
M191T36 190.993 35.806 0.600 1.756 54149414.195 11688351.283 83120775.454 5526406.173 0.651 -0.618 0.005 0.034
M191T427 191.068 426.934 7.120 1.479 836718.583 498981.047 147820.388 33880.900 5.660 2.501 0.005 0.034
M191T814_1 191.143 814.400 13.570 1.727 22879609.945 5408193.396 11184727.502 1299868.423 2.046 1.032 0.005 0.034
M192T102 192.159 101.888 1.700 1.284 5444805.521 4311716.802 877747.677 244032.767 6.203 2.633 0.005 0.034
M193T526 193.050 525.653 8.760 1.766 1866360.649 144201.445 2494591.803 232738.459 0.748 -0.419 0.005 0.034
M193T603 193.069 602.851 10.050 1.531 1037602.865 586246.155 163845.153 25422.887 6.333 2.663 0.005 0.034
M193T457 193.084 456.960 7.620 1.714 3133858.937 595691.013 1727911.713 341624.827 1.814 0.859 0.005 0.034
M193T789 193.122 789.182 13.150 1.627 24430143.472 840937.622 21410435.754 1520193.927 1.141 0.190 0.005 0.034
M194T62 193.990 61.912 1.030 1.722 41594100.950 12774743.706 12297408.788 5890873.557 3.382 1.758 0.005 0.034
M194T259 194.042 259.184 4.320 1.637 127679.944 105102.783 915786.726 432585.538 0.139 -2.842 0.005 0.034
M194T548 194.154 547.723 9.130 1.752 2792682.047 370729.665 1910180.722 143227.192 1.462 0.548 0.005 0.034
M195T81_2 195.099 81.050 1.350 1.199 20786550.404 3061975.841 57984057.654 39126278.792 0.358 -1.480 0.005 0.034
M195T358 195.123 358.490 5.970 1.756 11723628.401 709873.798 14189498.994 841140.549 0.826 -0.275 0.005 0.034
M195T548 195.157 547.699 9.130 1.795 209919.194 58546.355 58164.911 19326.273 3.609 1.852 0.005 0.034
M196T36_1 195.993 35.966 0.600 1.811 21071184.009 2857495.987 12133465.385 1973784.771 1.737 0.796 0.005 0.034
M196T587 196.052 587.157 9.790 1.839 739578.726 95678.363 462278.038 27015.993 1.600 0.678 0.005 0.034
M196T389 196.116 389.295 6.490 1.520 570233.549 253116.018 182706.547 77630.198 3.121 1.642 0.005 0.034
M197T443 197.092 442.956 7.380 1.330 1439746.124 920541.960 396220.286 123261.288 3.634 1.861 0.005 0.034
M198T144 198.037 144.268 2.400 1.658 531090.324 296153.184 1582183.648 489224.007 0.336 -1.575 0.005 0.034
M199T35 199.029 35.352 0.590 1.699 6282875.756 1208952.778 19021997.453 6305462.237 0.330 -1.598 0.005 0.034
M199T718 199.060 717.937 11.970 1.647 270323.696 90731.885 99871.204 26810.054 2.707 1.437 0.005 0.034
M200T480 199.988 480.382 8.010 1.172 182928410.062 175004125.258 22675267.059 7950718.807 8.067 3.012 0.005 0.034
M200T402_2 200.047 402.356 6.710 1.794 5977390621.915 79035919.789 6312969448.598 111179191.821 0.947 -0.079 0.005 0.034
M200T402_3 200.123 402.355 6.710 1.912 5909864.207 891979.109 10741046.951 966242.453 0.550 -0.862 0.005 0.034
M201T402 201.050 402.356 6.710 1.815 579462097.324 6090448.229 633585922.868 19909136.145 0.915 -0.129 0.005 0.034
M201T587 201.051 587.147 9.790 1.798 79970.429 19310.911 228987.998 56806.422 0.349 -1.518 0.005 0.034
M201T631 201.160 630.801 10.510 1.461 1232001.232 287029.622 836589.616 66015.950 1.473 0.558 0.005 0.034
M202T587 202.044 587.157 9.790 1.420 782478.573 88746.882 1367772.278 453023.082 0.572 -0.806 0.005 0.034
M202T357 202.144 357.370 5.960 1.679 1644464.224 606120.038 429366.441 191707.502 3.830 1.937 0.005 0.034
M203T225 203.050 224.697 3.740 1.639 2030371.364 1796471.881 23377309.437 11885489.424 0.087 -3.525 0.005 0.034
M203T550 203.110 549.518 9.160 1.700 115580.653 39929.792 327500.700 98798.148 0.353 -1.503 0.005 0.034
M203T99 203.103 99.009 1.650 1.693 2954972.254 1207519.796 509554.002 304325.331 5.799 2.536 0.005 0.034
M203T160 203.183 160.358 2.670 1.747 38363459.495 5900962.685 54697693.025 4541808.696 0.701 -0.512 0.005 0.034
M204T37 203.971 36.577 0.610 1.343 12698625.995 10207808.015 1028047.818 307615.121 12.352 3.627 0.005 0.034
M204T107 203.975 107.378 1.790 1.727 2539220.103 657180.383 1149147.559 68303.876 2.210 1.144 0.005 0.034
M204T160 204.186 160.411 2.670 1.505 5962426.054 3216953.591 1345769.269 206410.208 4.431 2.147 0.005 0.034
M205T36 205.045 35.637 0.590 1.765 9831545.427 932571.739 7429529.839 480049.520 1.323 0.404 0.005 0.034
M206T99 206.040 98.679 1.640 1.744 1706871.599 368924.974 745318.791 240513.425 2.290 1.195 0.005 0.034
M206T756 206.067 756.391 12.610 1.601 908009.852 255585.079 348190.153 219330.941 2.608 1.383 0.005 0.034
M208T275 208.008 274.524 4.580 1.103 15455479.020 16751169.867 1424140.314 352188.354 10.852 3.440 0.005 0.034
M208T36_2 208.045 36.430 0.610 1.993 1387825.363 117314.675 418109.814 72073.889 3.319 1.731 0.005 0.034
M208T815 208.072 814.546 13.580 1.827 1731767.083 196843.105 1008627.107 183350.548 1.717 0.780 0.005 0.034
M208T572 208.170 572.280 9.540 1.662 595303.845 218839.292 169408.836 71761.616 3.514 1.813 0.005 0.034
M209T108 208.817 107.938 1.800 1.842 881230.355 198325.437 2589653.502 573671.877 0.340 -1.555 0.005 0.034
M209T39 209.004 38.702 0.650 1.747 33286384.109 7977976.120 14991548.679 2416908.352 2.220 1.151 0.005 0.034
M209T36 209.028 36.313 0.610 1.720 3836453.764 1425670.785 873309.904 108440.055 4.393 2.135 0.005 0.034
M209T81_2 209.115 81.309 1.360 1.768 3063787.308 826953.391 7628164.499 1799740.393 0.402 -1.316 0.005 0.034
M210T735 210.185 734.721 12.250 1.350 2646173.376 310535.495 5966259.208 2863698.881 0.444 -1.173 0.005 0.034
M211T344 211.053 343.524 5.730 1.691 5512107.358 826368.127 3395979.554 700444.851 1.623 0.699 0.005 0.034
M211T457_2 211.095 456.858 7.610 1.563 1691307.673 623829.758 665332.204 202764.792 2.542 1.346 0.005 0.034
M211T747 211.169 747.284 12.450 1.354 23221434.925 13572102.816 7462572.361 798647.948 3.112 1.638 0.005 0.034
M212T102 212.206 102.249 1.700 1.362 1253270.781 87034.418 3369400.905 1804061.129 0.372 -1.427 0.005 0.034
M213T260 213.005 259.606 4.330 1.901 134588.543 71768.845 576271.442 104298.109 0.234 -2.098 0.005 0.034
M213T463 213.024 462.958 7.720 1.507 659437.038 269606.651 227099.771 133802.706 2.904 1.538 0.005 0.034
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M303T145 303.031 145.468 2.420 1.081 11565131.147 741752.570 13604030.834 2392751.122 0.850 -0.234 0.045 0.138
M303T505 303.177 504.908 8.420 1.322 10441799.901 1260759.081 8407555.129 1327399.937 1.242 0.313 0.045 0.138
M303T374 303.199 373.856 6.230 1.076 16470837.690 2270766.877 19431787.961 2869692.463 0.848 -0.238 0.045 0.138
M304T505 304.181 504.671 8.410 1.071 1613978.597 241464.837 1280409.261 337645.914 1.260 0.334 0.045 0.138
M304T391 304.176 391.144 6.520 1.277 2548312.116 1838888.327 545245.210 523810.754 4.674 2.225 0.045 0.138
M305T146 305.008 145.608 2.430 1.317 848300.057 129524.397 1493124.804 569638.720 0.568 -0.816 0.045 0.138
M307T397 307.129 397.110 6.620 1.232 49811.247 45718.687 221745.848 167928.611 0.225 -2.154 0.045 0.138
M310T145 309.986 145.468 2.420 1.325 16453948.187 2374865.382 11477190.569 3775772.008 1.434 0.520 0.045 0.138
M311T81 310.912 81.316 1.360 1.292 33155263.793 3113538.063 38281113.921 3649701.488 0.866 -0.207 0.045 0.138
M312T652 312.217 652.323 10.870 1.143 774043.549 538924.534 282659.727 141205.443 2.738 1.453 0.045 0.138
M314T505 314.158 504.976 8.420 1.068 519747.625 546735.236 1450433.059 1026002.951 0.358 -1.481 0.045 0.138
M315T141_2 315.004 140.709 2.350 1.306 4421519.119 1501088.552 8402232.240 3337401.255 0.526 -0.926 0.045 0.138
M315T721 315.133 720.641 12.010 1.323 853158.146 413537.766 2272068.912 1205501.614 0.376 -1.413 0.045 0.138
M316T254 316.137 253.777 4.230 1.168 87327676.068 66226481.817 25572439.086 14660671.575 3.415 1.772 0.045 0.138
M317T760 317.287 760.376 12.670 1.297 3873197.826 386309.140 3125776.566 577470.744 1.239 0.309 0.045 0.138
M319T511 318.698 511.337 8.520 1.354 78385.642 25033.805 220321.377 119862.148 0.356 -1.491 0.045 0.138
M319T605 319.263 604.749 10.080 1.270 167579.106 105885.021 343309.022 132059.324 0.488 -1.035 0.045 0.138
M324T543 324.004 543.409 9.060 1.527 200373.778 38242.533 413695.369 139092.480 0.484 -1.046 0.045 0.138
M324T693 324.129 693.289 11.550 1.072 5678540.398 4290013.001 2022336.372 1499684.818 2.808 1.490 0.045 0.138
M326T474 325.968 474.250 7.900 1.202 263444.766 218465.153 691102.351 393324.859 0.381 -1.391 0.045 0.138
M329T86 328.755 85.549 1.430 1.294 2608472.315 946799.325 1421007.574 577810.881 1.836 0.876 0.045 0.138
M330T765 330.246 765.126 12.750 1.252 10772918.772 2130183.126 7916411.447 1840573.822 1.361 0.444 0.045 0.138
M331T726 331.226 725.720 12.100 1.219 903685.013 618748.842 2038060.174 988666.335 0.443 -1.173 0.045 0.138
M333T608 333.144 607.668 10.130 1.203 2178680.733 1537162.276 5651779.342 3309213.444 0.385 -1.375 0.045 0.138
M334T592 334.147 592.015 9.870 1.255 314731.338 265664.576 1123325.285 748638.284 0.280 -1.836 0.045 0.138
M335T98 335.095 98.422 1.640 1.078 2497372.881 1108690.115 1431696.284 704603.048 1.744 0.803 0.045 0.138
M337T87 337.171 87.011 1.450 1.061 5953475.288 4012695.609 2348099.008 2136982.850 2.535 1.342 0.045 0.138
M337T818 337.168 818.445 13.640 1.289 65384809.499 20878203.186 37764798.522 15433508.066 1.731 0.792 0.045 0.138
M339T85 338.784 85.016 1.420 1.234 2344267.006 581787.189 1506033.915 613284.312 1.557 0.638 0.045 0.138
M341T786 341.196 786.114 13.100 1.328 1500570.364 460607.425 614521.866 643023.537 2.442 1.288 0.045 0.138
M341T760 341.316 759.850 12.660 1.310 1030178.756 140818.693 835790.022 108475.605 1.233 0.302 0.045 0.138
M342T453 341.655 453.339 7.560 1.390 897664.164 495820.475 262942.080 163027.104 3.414 1.771 0.045 0.138
M346T761_1 345.604 761.292 12.690 1.323 21427422.695 6414628.305 10688895.132 7219719.351 2.005 1.003 0.045 0.138
M347T482 347.159 482.036 8.030 1.274 162027.107 177589.149 623173.571 404538.644 0.260 -1.943 0.045 0.138
M350T468 350.206 467.608 7.790 1.351 6647956.585 1334376.841 3880280.268 1993047.569 1.713 0.777 0.045 0.138
M353T777 353.230 777.356 12.960 1.110 5594352.414 3572495.663 42261024.125 43239875.732 0.132 -2.917 0.045 0.138
M354T519 354.171 518.607 8.640 1.168 923500.572 553876.329 379019.237 225609.627 2.437 1.285 0.045 0.138
M356T683 356.219 682.946 11.380 1.089 1219182.085 348008.974 885426.860 208904.154 1.377 0.461 0.045 0.138
M358T484 358.221 484.333 8.070 1.483 1231427.810 452205.217 505871.178 262856.201 2.434 1.284 0.045 0.138
M359T84 358.841 84.004 1.400 1.341 7949929.025 1409528.853 5877129.166 1148591.408 1.353 0.436 0.045 0.138
M361T87 361.208 86.565 1.440 1.060 2984176.937 2062182.846 5519940.536 2449575.467 0.541 -0.887 0.045 0.138
M364T647 364.219 647.019 10.780 1.275 5605898.870 4744261.488 12890300.796 5104653.342 0.435 -1.201 0.045 0.138
M365T86 364.915 86.016 1.430 1.214 4834213.133 2450817.210 2416407.612 513164.143 2.001 1.000 0.045 0.138
M372T345 372.102 345.277 5.750 1.275 6894562.607 3928510.908 2663160.388 991016.227 2.589 1.372 0.045 0.138
M373T800 373.127 800.130 13.340 1.249 4130011.839 2468792.917 1597754.862 430995.481 2.585 1.370 0.045 0.138
M380T81 379.904 80.729 1.350 1.337 1829404.647 424418.766 1272716.399 247512.071 1.437 0.523 0.045 0.138
M381T81 380.898 81.303 1.360 1.070 5110892.373 2082836.955 3083258.465 1430512.564 1.658 0.729 0.045 0.138
M381T713 381.315 712.963 11.880 1.219 1007790.102 407192.971 578038.848 172433.884 1.744 0.802 0.045 0.138
M392T735_1 391.833 734.688 12.240 1.428 560918.631 131365.756 1882618.142 1022257.980 0.298 -1.747 0.045 0.138
M395T814 395.309 814.321 13.570 1.124 85712.321 151831.518 499421.645 456414.742 0.172 -2.543 0.045 0.138
M399T87 399.009 87.071 1.450 1.421 903424.382 369637.326 1581047.731 385444.180 0.571 -0.807 0.045 0.138
M399T792 399.329 791.808 13.200 1.239 3458290.912 2413123.753 1017212.267 402139.923 3.400 1.765 0.045 0.138
M403T686 403.320 685.918 11.430 1.113 1219034.033 332136.266 879852.847 222946.988 1.385 0.470 0.045 0.138
M411T92 411.051 91.870 1.530 1.213 1168100.180 845955.534 326033.591 215918.574 3.583 1.841 0.045 0.138
M413T102 413.164 102.355 1.710 1.099 185365.072 328736.501 5306105.255 6133361.216 0.035 -4.839 0.045 0.138
M414T396 414.144 395.915 6.600 1.241 129664.084 55007.965 320527.631 182811.982 0.405 -1.306 0.045 0.138
M422T83 421.886 83.500 1.390 1.332 7673955.699 2840533.969 4223290.813 1156097.968 1.817 0.862 0.045 0.138
M430T533_1 430.242 533.307 8.890 1.296 45645912.383 4867172.704 36000190.604 7543218.456 1.268 0.342 0.045 0.138
M437T817 437.192 816.648 13.610 1.353 41742870.715 6281214.218 29299321.408 8716465.699 1.425 0.511 0.045 0.138
M449T85 448.753 84.542 1.410 1.306 3619789.889 590754.673 4680465.677 774968.400 0.773 -0.371 0.045 0.138
M453T816 453.278 816.260 13.600 1.213 13210508.135 6327857.924 6649139.474 2485783.178 1.987 0.990 0.045 0.138
M458T66_2 458.405 66.203 1.100 1.194 1819562.113 267539.742 2431103.405 591537.937 0.748 -0.418 0.045 0.138
M466T798 466.227 797.814 13.300 1.076 1981668.192 267061.596 1737232.723 141664.156 1.141 0.190 0.045 0.138
M468T805_2 468.320 805.443 13.420 1.247 147163039.887 65369420.093 70249789.804 39372308.077 2.095 1.067 0.045 0.138
M471T668 471.450 668.319 11.140 1.568 976014.254 210751.459 5756753.702 3025578.454 0.170 -2.560 0.045 0.138
M474T603 474.325 603.168 10.050 1.333 282140.823 113845.750 558943.318 217711.762 0.505 -0.986 0.045 0.138
M476T804 476.276 804.137 13.400 1.162 32412367.247 13158055.043 19166606.641 6473838.201 1.691 0.758 0.045 0.138
M488T648 488.298 647.614 10.790 1.395 107064.271 155959.075 723583.066 478512.076 0.148 -2.757 0.045 0.138
M491T698 491.091 697.955 11.630 1.346 300141.758 71250.733 207095.065 38887.199 1.449 0.535 0.045 0.138
M492T103 492.131 102.612 1.710 1.221 1867123.924 1366404.717 424268.795 568358.523 4.401 2.138 0.045 0.138
M493T577 493.223 577.412 9.620 1.305 209956.748 28894.767 261615.136 37785.961 0.803 -0.317 0.045 0.138
M493T791 493.312 791.315 13.190 1.232 2652249.478 1528706.038 955707.277 782526.744 2.775 1.473 0.045 0.138
M494T812_2 494.330 812.075 13.530 1.063 324107467.246 300700440.896 79128515.065 66889721.187 4.096 2.034 0.045 0.138
M495T823_1 494.617 822.755 13.710 1.073 1049358.454 867986.546 305353.378 316120.419 3.437 1.781 0.045 0.138
M512T87 511.922 86.578 1.440 1.213 3839925.371 1402168.502 5598245.228 1165518.523 0.686 -0.544 0.045 0.138
M515T698 515.142 698.370 11.640 1.449 94438.684 50501.898 561909.972 350580.392 0.168 -2.573 0.045 0.138
M516T812_2 516.305 812.043 13.530 1.215 37111964.085 26048528.876 11285636.449 5919779.353 3.288 1.717 0.045 0.138
M517T79 516.996 78.846 1.310 1.063 1540180.114 841215.626 2986594.462 1612649.410 0.516 -0.955 0.045 0.138
M520T699 520.327 699.137 11.650 1.399 1326226.613 314911.283 3168375.338 1461841.544 0.419 -1.256 0.045 0.138
M521T85 520.733 84.506 1.410 1.491 2492060.862 561661.695 4020293.195 933419.606 0.620 -0.690 0.045 0.138
M527T84 526.771 84.073 1.400 1.236 2948203.895 888694.895 4030904.372 631201.543 0.731 -0.451 0.045 0.138
M530T818 530.358 817.703 13.630 1.026 3078075.988 2054012.293 8295154.086 6570393.532 0.371 -1.430 0.045 0.138
M531T84_1 530.764 84.045 1.400 1.251 2201774.834 578812.501 3315603.618 935025.551 0.664 -0.591 0.045 0.138
M538T88_3 538.205 87.572 1.460 1.179 4121003.444 2916513.600 10614138.243 6395684.787 0.388 -1.365 0.045 0.138
M551T663 551.281 662.933 11.050 1.121 315623.785 113986.962 749292.167 493047.128 0.421 -1.247 0.045 0.138
M564T810_2 564.303 809.677 13.490 1.203 135143975.632 89912088.061 42506056.076 37197501.122 3.179 1.669 0.045 0.138
M564T801_1 564.303 800.982 13.350 1.258 22600489.854 16661233.698 4733743.331 5313207.418 4.774 2.255 0.045 0.138
M566T810 566.312 810.287 13.500 1.359 8314194.831 3778131.633 3489578.860 1671597.338 2.383 1.252 0.045 0.138
M570T836_2 570.356 835.578 13.930 1.142 56013644.007 29959152.621 22161105.284 24087453.759 2.528 1.338 0.045 0.138
M571T836_1 571.345 835.587 13.930 1.323 24049704.153 8084706.534 10847897.856 8685162.452 2.217 1.149 0.045 0.138
M580T809 580.277 809.271 13.490 1.211 1945737.394 1440901.765 454294.732 570553.159 4.283 2.099 0.045 0.138
M583T703_1 583.254 702.917 11.720 1.138 2241045.964 1323812.602 6701732.114 4914994.157 0.334 -1.580 0.045 0.138
M590T836_2 590.320 835.595 13.930 1.332 284835398.579 87357346.387 134015646.812 101611798.793 2.125 1.088 0.045 0.138
M592T836 592.325 835.895 13.930 1.351 17311575.703 4701433.922 8105790.128 6440082.297 2.136 1.095 0.045 0.138
M595T84_1 594.756 84.041 1.400 1.276 2647517.353 711805.771 3825352.997 871837.391 0.692 -0.531 0.045 0.138
M595T88_1 595.148 87.573 1.460 1.311 4089572.678 2810902.743 11812372.773 6469975.941 0.346 -1.530 0.045 0.138
M602T80 601.882 80.085 1.330 1.270 1255437.005 794167.218 2177722.492 397341.976 0.576 -0.795 0.045 0.138
M604T602_8 603.790 602.105 10.040 1.158 4226171.258 1163229.012 7938246.114 3962239.093 0.532 -0.909 0.045 0.138
M607T691_1 607.249 691.380 11.520 1.271 1072152.875 575561.060 3092639.291 1855714.095 0.347 -1.528 0.045 0.138
M613T503_3 613.350 503.098 8.380 1.187 3659170.098 1366413.895 1505796.951 1860177.751 2.430 1.281 0.045 0.138
M616T102 616.208 102.372 1.710 1.154 5823.976 1944.844 1211039.782 1348116.281 0.005 -7.700 0.045 0.138
M618T737 618.262 737.201 12.290 1.126 280746.740 341092.742 1664500.001 1567662.727 0.169 -2.568 0.045 0.138
M619T601_3 618.601 601.123 10.020 1.445 630015.438 193596.265 1733965.592 817738.237 0.363 -1.461 0.045 0.138
M652T713 652.367 712.866 11.880 1.177 682775.038 549373.918 169246.584 94086.115 4.034 2.012 0.045 0.138
M664T602_3 663.750 602.167 10.040 1.418 3383265.018 1169189.751 9080230.672 4349114.769 0.373 -1.424 0.045 0.138
M664T602_6 663.863 602.325 10.040 1.026 18023315.192 5826720.582 37032686.203 24393435.342 0.487 -1.039 0.045 0.138
M664T602_10 664.066 602.306 10.040 1.225 19224320.287 2955735.081 13102469.932 5502705.529 1.467 0.553 0.045 0.138
M685T84_2 684.807 83.501 1.390 1.298 18365242.590 11616077.861 5768499.509 1363519.099 3.184 1.671 0.045 0.138
M729T635_2 729.412 634.746 10.580 1.132 1009519.029 671981.065 395075.401 218219.816 2.555 1.353 0.045 0.138
M731T84_2 730.743 84.000 1.400 1.390 1864819.313 371769.496 2999129.961 854925.646 0.622 -0.686 0.045 0.138
M732T819 731.611 818.914 13.650 1.197 18174104.392 13262556.219 65872478.236 48731087.811 0.276 -1.858 0.045 0.138
M745T820_2 744.580 819.522 13.660 1.122 13027661.661 8936752.556 37189491.503 26695567.448 0.350 -1.513 0.045 0.138
M745T787_2 744.597 786.518 13.110 1.345 4337044.752 3433683.518 13576980.606 7303216.582 0.319 -1.646 0.045 0.138
M755T707_1 754.622 706.954 11.780 1.401 73357.067 15325.834 302140.656 184564.621 0.243 -2.042 0.045 0.138
M763T32_2 762.592 31.764 0.530 1.179 932359.179 1677860.317 2966665.946 1428084.432 0.314 -1.670 0.045 0.138
M763T83_2 762.827 82.597 1.380 1.194 1071966.196 323139.215 1590441.184 445949.170 0.674 -0.569 0.045 0.138
M771T397_1 770.536 397.133 6.620 1.186 101714.083 63852.360 206890.203 93017.452 0.492 -1.024 0.045 0.138
M771T80_3 770.857 80.086 1.330 1.191 84402735.708 16880339.242 59852962.075 19989868.749 1.410 0.496 0.045 0.138
M779T80_3 779.333 79.579 1.330 1.495 1143851.254 203157.871 3800416.981 1873409.267 0.301 -1.732 0.045 0.138
M786T785_1 785.578 784.774 13.080 1.347 12199767.658 3033411.691 36418284.196 20871260.518 0.335 -1.578 0.045 0.138
M791T603_2 790.963 602.929 10.050 1.404 291522.764 146147.123 620300.600 221181.835 0.470 -1.089 0.045 0.138
M792T486_11 792.406 485.713 8.100 1.002 1697172.794 2597173.723 11084849.569 12523638.429 0.153 -2.707 0.045 0.138
M795T543 794.753 543.380 9.060 1.235 528421.667 396841.479 123994.596 92527.772 4.262 2.091 0.045 0.138
M802T832_1 801.978 832.096 13.870 1.120 272988.586 273518.497 843699.938 608315.591 0.324 -1.628 0.045 0.138
M814T80_2 813.840 80.067 1.330 1.203 279354.140 136410.341 604799.816 313137.982 0.462 -1.114 0.045 0.138
M825T601_3 825.304 601.426 10.020 1.289 155076.698 123184.037 565238.797 365484.299 0.274 -1.866 0.045 0.138
M829T602_2 829.331 602.330 10.040 1.176 7986917.581 6755270.263 1714163.350 919602.911 4.659 2.220 0.045 0.138
M830T602_14 830.309 602.351 10.040 1.333 3680498.586 1882449.587 1421744.970 689441.212 2.589 1.372 0.045 0.138
M833T819_2 832.592 818.717 13.650 1.340 4228291.634 3067414.975 13576792.929 7621826.519 0.311 -1.683 0.045 0.138
M838T597_6 838.265 597.414 9.960 1.441 292010.453 156348.952 666118.650 240046.253 0.438 -1.190 0.045 0.138
M839T80_3 838.846 80.085 1.330 1.371 259150736.180 133529407.065 100221520.030 10974208.002 2.586 1.371 0.045 0.138
M869T669_8 869.126 668.952 11.150 1.255 1482211.476 631040.288 3004417.090 1355501.883 0.493 -1.019 0.045 0.138
M869T669_11 869.253 668.657 11.140 1.299 1370588.287 387803.850 3114446.717 1569928.323 0.440 -1.184 0.045 0.138
M871T79_2 870.959 78.872 1.310 1.161 6134044.354 5776647.783 900797.123 549965.042 6.810 2.768 0.045 0.138
M873T80_1 872.801 80.082 1.330 1.298 1013885.492 654832.812 1905021.381 505432.510 0.532 -0.910 0.045 0.138
M885T668_2 885.059 667.775 11.130 1.311 262939.445 226143.469 607898.909 219060.709 0.433 -1.209 0.045 0.138
M939T102_1 939.302 102.361 1.710 1.125 34738.926 14675.761 967612.457 1082426.556 0.036 -4.800 0.045 0.138
M963T680_1 962.596 679.609 11.330 1.376 229568.457 85893.080 1314809.944 905316.259 0.175 -2.518 0.045 0.138
M972T665_5 971.950 665.113 11.090 1.127 1620800.096 1363626.146 414776.563 300108.443 3.908 1.966 0.045 0.138
M980T667_17 980.375 667.356 11.120 1.262 2281312.065 812420.867 1181507.399 697388.140 1.931 0.949 0.045 0.138
M980T667_18 980.397 667.220 11.120 1.387 1488956.989 600980.576 4186934.910 2143023.779 0.356 -1.492 0.045 0.138
M986T663_1 985.843 663.407 11.060 1.091 466151.765 354651.144 157219.096 120283.299 2.965 1.568 0.045 0.138
M986T664_4 986.069 663.538 11.060 1.268 2610184.495 1409235.331 1043770.716 547296.949 2.501 1.322 0.045 0.138
mz：质核比；rt：保留时间(以秒为单位)；rtmin：保留时间(以分钟为单位)；*_VIP：VIP值；mean_*：平均值；sd_*：标准差；fold change：倍性变化；log2(FC)：倍性变化的log2值；pvalue：统计学p值；FDR：pvalue校正值
以下为差异待鉴定代谢物统计结果：
图：差异代谢物统计柱状图
代谢物上下调关系
updownstats.csv